Cassiopeia
Cassiopeia Portrait
Cassiopeia
Patch 10.22 AD Carry

Cassiopeia Build and Runes

Cassiopeia build guide, best Cassiopeia runes and items to use in Patch 10.22. This Cassiopeia AD Carry build for LoL is based on win rates and meta popularity. Use this Cassiopeia build guide to statistically win more games in League.

Serpentine Grace
Noxious Blast
Miasma
Twin Fang
Petrifying Gaze

Games analyzed

11,778

Win %

51.71%

Pick %

0.47%

Ban %

3.17%

Kills

6.43

Deaths

5.62

Assists

6.44

Skill Priority (10,395 Games)

Twin Fang
Noxious Blast
Miasma
Noxious Blast
Miasma
Twin Fang
Petrifying Gaze
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Spells & Items

Summoner Spells

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Starting Build (Winrate)

Health Potion
Warding Totem (Trinket)
Doran's Ring

End-game Build (Winrate)

Archangel's Staff
Rylai's Crystal Scepter
Liandry's Torment
Zhonya's Hourglass
Void Staff
Rabadon's Deathcap

Runes

Cassiopeia

Primary

Precision

Press the Attack
Lethal Tempo
Fleet Footwork
Conqueror
Overheal
Triumph
Presence of Mind
Legend: Alacrity
Legend: Tenacity
Legend: Bloodline
Coup de Grace
Cut Down
Last Stand
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Secondary

Domination

Cheap Shot
Taste of Blood
Sudden Impact
Zombie Ward
Ghost Poro
Eyeball Collection
Ravenous Hunter
Ingenious Hunter
Relentless Hunter
Ultimate Hunter
Adaptive
AttackSpeed
CDRScaling
Adaptive
Armor
MagicRes
HealthScaling
Armor
MagicRes

Cassiopeia build in Patch 10.22

Find out the best Cassiopeia build by following the statistics on this page. You are more likely to perform better in your games by following this build.

The most winning Cassiopeia build involves a skill priority of Twin Fang Twin Fang Noxious Blast Noxious Blast Miasma Miasma , running a Precision | Domination rune set-up and taking Flash Flash Heal Heal as summoner spells.

Start your Cassiopeia build off by running Health Potion Health Potion Warding Totem (Trinket) Warding Totem (Trinket) Doran's Ring Doran's Ring , progressing that into Archangel's Staff Archangel's Staff Rylai's Crystal Scepter Rylai's Crystal Scepter Liandry's Torment Liandry's Torment Zhonya's Hourglass Zhonya's Hourglass Void Staff Void Staff Rabadon's Deathcap Rabadon's Deathcap , But remember to pick the correct situational items depending on game factors such as enemy composition.

Cassiopeia runes in Patch 10.22

Primary Runes

Here are the best Cassiopeia runes for this build. Take Press the Attack Press the Attack as your keystone in the Precision rune tree. The remaining slots in your primary tree should be the Presence of Mind Presence of Mind Legend: Tenacity Legend: Tenacity Coup de Grace Coup de Grace runes.

Secondary Runes

Cassiopeia's secondary runes should be in the Domination rune tree, taking the Taste of Blood Taste of Blood Ravenous Hunter Ravenous Hunter runes.

As far as your shards go, take AdaptiveAdaptive AdaptiveAdaptive ArmorArmor . Following these runes for Cassiopeia will help you in your games. Make sure to make situational changes to your runes depending on team comps and counters.

While you're looking at our Cassiopeia build

Check out our lane tier lists