Cassiopeia build guide, best Cassiopeia runes and items to use in Patch 10.22. This Cassiopeia AD Carry build for LoL is based on win rates and meta popularity. Use this Cassiopeia build guide to statistically win more games in League.
Find out the best Cassiopeia build by following the statistics on this page. You are more likely to perform better in your games by following this build.
The most winning Cassiopeia build involves a skill priority of Twin Fang Noxious Blast Miasma , running a Precision | Domination rune set-up and taking Flash Heal as summoner spells.
Start your Cassiopeia build off by running Health Potion Warding Totem (Trinket) Doran's Ring , progressing that into Archangel's Staff Rylai's Crystal Scepter Liandry's Torment Zhonya's Hourglass Void Staff Rabadon's Deathcap , But remember to pick the correct situational items depending on game factors such as enemy composition.
Here are the best Cassiopeia runes for this build. Take Press the Attack as your keystone in the Precision rune tree. The remaining slots in your primary tree should be the Presence of Mind Legend: Tenacity Coup de Grace runes.
Cassiopeia's secondary runes should be in the Domination rune tree, taking the Taste of Blood Ravenous Hunter runes.
As far as your shards go, take Adaptive Adaptive Armor . Following these runes for Cassiopeia will help you in your games. Make sure to make situational changes to your runes depending on team comps and counters.
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