Patch 10.22 AD Carry

Vayne Build and Runes

Vayne build guide, best Vayne runes and items to use in Patch 10.22. This Vayne AD Carry build for LoL is based on win rates and meta popularity. Use this Vayne build guide to statistically win more games in League.

Games analyzed

244,013

Win %

51.55%

Pick %

9.69%

Ban %

7.51%

Kills

7.33

Deaths

5.91

Assists

5.89

Skill Priority (179,438 Games)

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Spells & Items

Summoner Spells

Starting Build (Winrate)

End-game Build (Winrate)

Runes

Primary

Precision

Secondary

Sorcery

Other AD Carry champions

Ashe

51.6%See build

Jhin

52%See build

Samira

51.9%See build

Senna

50.5%See build

Caitlyn

50.1%See build

Vayne

51.5%See build

Kog'Maw

52.3%See build

Draven

50.8%See build

Vayne build in Patch 10.22

Find out the best Vayne build by following the statistics on this page. You are more likely to perform better in your games by following this build.

The most winning Vayne build involves a skill priority of Silver Bolts Tumble Tumble Condemn Condemn , running a Precision | Sorcery rune set-up and taking Flash Flash Heal Heal as summoner spells.

Start your Vayne build off by running Health Potion Warding Totem (Trinket) Doran's Blade , progressing that into Berserker's Greaves Blade of the Ruined King Guinsoo's Rageblade Phantom Dancer Infinity Edge Mercurial Scimitar , But remember to pick the correct situational items depending on game factors such as enemy composition.

Vayne runes in Patch 10.22

Primary Runes

Here are the best Vayne runes for this build. Take Press the Attack as your keystone in the Precision rune tree. The remaining slots in your primary tree should be the Triumph Triumph Legend: Alacrity Coup de Grace runes.

Secondary Runes

Vayne's secondary runes should be in the Sorcery rune tree, taking the Nimbus Cloak Gathering Storm runes.

As far as your shards go, take AttackSpeed Adaptive Armor Armor . Following these runes for Vayne will help you in your games. Make sure to make situational changes to your runes depending on team comps and counters.

While you're looking at our Vayne build